Assuming this is a bipolar transistor, they are most common.
You are correct, 100V/25 amps are the max ratings, and should not be approached too closely.
Assume you want to operate it at 20 amps. Look up on the spec sheet for HFE. This is the current gain. Let's say it is 50 minimum. Also check what current it is tested at, if not at 20 amps, we may have to look at some curves to guess what it would be at 20 amps.
So if HFE is 50, then base current is 20/50 or 400mA, which is the maximum current you need to get 50a in the collector.
For this discussion to move any further, I'd need to know a lot of detail, with the first item, is this a saturated application, like a switch or a linear application, like an amplifier.
Watch out for heat. In the example above, 20 amps and, say, 50 volts is 1000 watts, a huge amount of power that would require a very large heat sink.